Biosensing
is truly a hot area of research today but it is not really new. It is basically
of two types physical and chemical. Physical biosensors are developed based on
physical parameters and therefore taste physical quantities. However, chemical
biosensors are based on chemical parameters and taste chemical quantities.
Chemical biosensing is indeed one of the top areas of research and therefore
you can find a lot of science and technology online articles dealing with this
important subject. More specifically, taste sensing, glucose detection &
diabetes control, to mention a few are the main subjects of the majority of science
and technology news updates.
Nanotechnology
and Biosensors
One
of the top areas of research is the application of nanotechnology to
biosensors. Nanotechnology is simply technology at the nanoscale. This involves
measurements at a level below the microscopic level. At this level, matters
exhibit rare characteristics. In other words, such rare characteristics become
common at the nanoscale. Nanotechnology is applied to biosensors, specifically
to taste sensing biosensors. Taste cells and receptor based biosensors are a
major field of research today. The reason for the numerous researches in this
field is their relevance in chemical sensing and researches in order to ensure
taste signal transduction mechanisms.
Taste
receptors development depends on greatly nanotechnology. This is simply because
nanotechnology is employed in developing small arrays of taste receptors and
such nano-fabrications make it easy to develop biosensors that consist of a lot
of taste cells and receptors. With multiple taste cells and receptors, the
biosensors would be more efficient.
More
interestingly, taste receptors are developed in such a way that they can
ascertain specific chemical signal which various taste compounds and substances
present. Their potency exceeds that of most artificial devices available today.
Because
of the effectiveness of taste sensors, they are being research upon as they
hold promises for the development of chemical sensors. However, there are
barriers to overcome in order to have this goal achieved. One of the major
barriers that must be overcome for the successful development of taste sensors
is the development of functional taste cells and receptors that would make up
for the need to build sensing components used in chemical sensing.
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Mechanism of Biosensing |
Relevance
of Biosensors
Biosensors
are very relevant in various fields of study. However, to apply biosensors and
to get the desired results, it is necessary to know the limits of chemical
sensors. Interestingly, chemical sensors do have limit, as do taste sensing
biosensors. The limit of detection (LOD) of chemical sensors are stated and
defined in the IUPAC guidelines. The guidelines also state the sensitivity of
chemical sensors. Biosensors are generally applied in the monitoring of glucose
level and the control of diabetes. Moreover, it is applied in various fields
including the food and beverage industry, environmental, medical diagnostics,
pharmaceuticals, agriculture. Biosensors are also applied in tissue
engineering, to mention a few. Taste sensors are widely applicable in areas
where sensitivity is required such as in the manufacturing of drugs,
agriculture and in production of chemicals.
You may like to read:ETHICAL ASPECTS OFNANOTECHNOLOGY
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For Further Reading
Wu et al., (2014) Recent advances intaste cell- and receptor-based biosensors
Haruyama T (2003) Micro- andnanobiotechnology for biosensing cellular responses
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